The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance
- Authors:Jennifer A. Doudna, Samuel H. Sternberg Houghton Mifflin Harcourt
- Publication Date:October 12, 2017
- Type:Handbooks
- DOL:10.1016/j.hfc.2018.03.008.
- Publication On:Heart Fail Clin.
- Volume/Issue:14/(3)
Abstract
Within the last years, exercise training and rehabilitation as add-on to medical treatment has become an emerging field in pulmonary hypertension. Owing to the beneficial effects of exercise training in pulmonary hypertension, the new European Respiratory Society/European Society of Cardiology guidelines for pulmonary hypertension recommended a supervised and closely monitored exercise and respiratory training/rehabilitation as add-on to medical therapy (class IIa, level of evidence B). In this article, different training modalities, effects of exercise training, possible pathobiological mechanisms of action, and future research questions are discussed.
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References
- Cashman K.D. Vitamin D requirements for the future-lessons learned and charting a path forward. Nutrients. 2018;10:533 doi: 10.3390/nu10050533. - DOI - PMC - PubMed
- Cashman K.D., Ritz C., Kiely M. Odin Collaborators. Improved dietary guidelines for vitamin D: Application of Individual Participant Data (IPD)-level meta-regression analyses. Nutrients. 2017;9:469 doi: 10.3390/nu9050469. - DOI - PMC - PubMed
- Pilz S., März W., Cashman K.D., Kiely M.E., Whiting S.J., Holick M.F., Grant W.B., Pludowski P., Hiligsmann M., Trummer C., et al. Rationale and plan for vitamin D food fortification: A review and guidance paper. Front. Endocrinol. 2018;9:373. doi: 10.3389/fendo.2018.00373. - DOI - PMC - PubMed